The ESS Meridian is the space ship where the story takes place on. It is the first interstellar colonization ship on its way to a planet named Tau Ceti. Most of the crew was put into hyper sleep in cryocabins but some of them stayed awake to guard the ship. Free from the rules and laws on earth they started to do forbidden research and experiments, they created live and turned themselves into monsters. One of them went so far that the ship was overrun by what he created his name was Wagner.
The ESS Meridian's hologram can be seen in Dead Effect 2.
The ESS Meridian's shape in the starting screen of Dead Effect 1 and the ESS Meridian's hologram in Dead Effect 2 is different.